Deciphering the single-cell transcriptome network in keloids with intra-lesional injection of triamcinolone acetonide combined with 5-fluorouracil

Deciphering the single-cell transcriptome network in keloids with intra-lesional injection of triamcinolone acetonide combined with 5-fluorouracil

ObjectivesKeloid is a highly aggressive fibrotic disease resulting from excessive extracellular matrix deposition after dermal injury. Intra-lesional injection of triamcinolone acetonide (TAC) in combination with 5-fluorouracil (5-FU) is a commonly used pharmacological regimen and long-term repeated...

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Bibliographic Details
Main Authors: Yijun Xia, Youbin Wang, Yan Hao, Mengjie Shan, Hao Liu, Zhengyun Liang, Xinwen Kuang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
triamcinolone acetonide
5-fluorouracil
keloid
scRNA
transcriptome
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1106289/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1106289/full

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