PLOD3 facilitated T cell activation in the colorectal tumor microenvironment and liver metastasis by the TNF-α/ NF-κB pathway

PLOD3 facilitated T cell activation in the colorectal tumor microenvironment and liver metastasis by the TNF-α/ NF-κB pathway

Abstract Background Colorectal cancer (CRC) has been the third most prevalent cancer worldwide. Liver metastasis is the critical factor for the poor prognosis of CRC. Here, we investigated the expression and role of PLOD3 in CRC. Methods Different liver metastasis models were established by injectin...

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Bibliographic Details
Main Authors: Min Ding, Cheng Wang, Junhong Hu, Junjun She, Ruoyu Shi, Yixuan Liu, Qi Sun, Haojun Xu, Guoren Zhou, Wenlan Wu, Hongping Xia
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Translational Medicine
Subjects:
PLOD3
Colorectal cancer
Liver metastasis
Proliferation
NF-κB
Online Access:https://doi.org/10.1186/s12967-023-04809-w

Internet

https://doi.org/10.1186/s12967-023-04809-w

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