3D genome organization links non-coding disease-associated variants to genes

Genome sequencing has revealed over 300 million genetic variations in human populations. Over 90% of variants are single nucleotide polymorphisms (SNPs), the remainder include short deletions or insertions, and small numbers of structural variants. Hundreds of thousands of these variants have been a...

Full description

Bibliographic Details
Main Authors: Gisela Orozco, Stefan Schoenfelder, Nicolas Walker, Stephan Eyre, Peter Fraser
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.995388/full