TGFB1 +869 T > C (rs1800470) variant is independently associated with susceptibility, laboratory activity, and TGF-β1 in patients with systemic lupus erythematosus

TGFB1 +869 T > C (rs1800470) variant is independently associated with susceptibility, laboratory activity, and TGF-β1 in patients with systemic lupus erythematosus

The aim of this study was to evaluate the association of the +869 T > C (rs1800470) and −509 C > T (rs1800469) TGFB1 variants, individually or in haplotypes structure, with susceptibility, autoantibodies, disease activity, and TGF-β1 plasma levels in patients with systemic lupus erythematosus...

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Bibliographic Details
Main Authors: Nicole Perugini Stadtlober, Tamires Flauzino, Lorena Flor da Rosa Franchi Santos, Tatiana Mayumi Veiga Iriyoda, Neide Tomimura Costa, Marcell Alysson Batisti Lozovoy, Edna Maria Vissoci Reiche, Andréa Name Colado Simão
Format: Article
Language:English
Published: Taylor & Francis Group 2021-11-01
Series:Autoimmunity
Subjects:
systemic lupus erythematosus
transforming growth factor-beta 1
rs1800470
rs18004469
sledai
Online Access:http://dx.doi.org/10.1080/08916934.2021.1975680

Internet

http://dx.doi.org/10.1080/08916934.2021.1975680

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