Impact of Albumin Binding Function on Pharmacokinetics and Pharmacodynamics of Furosemide

Impact of Albumin Binding Function on Pharmacokinetics and Pharmacodynamics of Furosemide

<i>Background and Objectives</i>: Albumin binding of the loop diuretic furosemide forms the basis for its transport to the kidney and subsequent tubular secretion, which is a prerequisite for its therapeutic effects. Accordingly, high albumin concentrations should result in higher effica...

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Bibliographic Details
Main Authors: Gerd Klinkmann, Sebastian Klammt, Malte Jäschke, Jörg Henschel, Martin Gloger, Daniel A. Reuter, Steffen Mitzner
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Medicina
Subjects:
albumin binding capacity
critical care
de-resuscitation
diuretics
fluid accumulation
fluid overload
Online Access:https://www.mdpi.com/1648-9144/58/12/1780

Internet

https://www.mdpi.com/1648-9144/58/12/1780

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