AROMATASE INHIBITORS IN BREAST CANCER THERAPY

Aromatase is an enzyme complex which is assigned in the last step of estrogen biosynthesis; it increases total estrogen levels by converting androgens to estrogens in tissues like breast, ovary, testis, placenta, brain and adipose. Estrogen causes increased proliferation of tumor cells. It has been...

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Bibliographic Details
Main Authors: Hande Karahan, Emine Pelin Kelicen
Format: Article
Language:English
Published: Galenos Publishing House 2011-04-01
Series:European Journal of Breast Health
Subjects:
Online Access: http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/aromatase-nhbtors-n-breast-cancer-therapy/42456