Methods to evaluate the impact of SARS-CoV-2 nucleocapsid mutations on antigen detection by rapid diagnostic tests

Methods to evaluate the impact of SARS-CoV-2 nucleocapsid mutations on antigen detection by rapid diagnostic tests

Mutations in the nucleocapsid of SARS-CoV-2 may interfere with antigen detection by diagnostic tests. We used several methods to evaluate the effect of various SARS-CoV-2 nucleocapsid mutations on the performance of the Panbio™ and BinaxNOW™ lateral flow rapid antigen tests and a prototype high-thro...

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Bibliographic Details
Main Authors: Bryan C Tieman, Stephen Kovacs, Mary A Rodgers, Aurash Mohaimani, Svetoslava Gregory, David Christensen, Jeffrey A Moore, Lici Schurig-Briccio, James Hartnett, Alak Kar, Aaron Leeman, Angel Palmer, Lauren Rogers, Brian Dragoo, Steven Muszynski, Deborah Noblesmith, Samantha Gardner, Abigail Snipe-Bushey, Anna Kill, Xinxin Luo, Sneha Cherukuri, Tracey Rae, Christopher C Marohnic, Gavin A Cloherty, Anthony Scott Muerhoff, Philip M Hemken
Format: Article
Language:English
Published: Future Science Ltd 2022-09-01
Series:BioTechniques
Subjects:
antigen
BinaxNOW
immunoassay
lateral flow assay
nucleocapsid
Panbio
Online Access:https://www.future-science.com/doi/10.2144/btn-2022-0020

Internet

https://www.future-science.com/doi/10.2144/btn-2022-0020

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