Genetic associations with psychosis and affective disturbance in Alzheimer's disease

Genetic associations with psychosis and affective disturbance in Alzheimer's disease

Abstract INTRODUCTION Individuals with Alzheimer's disease (AD) commonly experience neuropsychiatric symptoms of psychosis (AD+P) and/or affective disturbance (depression, anxiety, and/or irritability, AD+A). This study's goal was to identify the genetic architecture of AD+P and AD+A, as w...

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Main Authors: Inga Margret Antonsdottir, Byron Creese, Lambertus Klei, Mary Ann A. DeMichele‐Sweet, Elise A. Weamer, Pablo Garcia‐Gonzalez, Marta Marquie, Mercè Boada, Emilio Alarcón‐Martín, Sergi Valero, NIA‐LOAD Family Based Study Consortium, Alzheimer's Disease Genetics Consortium (ADGC), AddNeuroMed Consortium, Yushi Liu, Basavaraj Hooli, Dag Aarsland, Geir Selbaek, Sverre Bergh, Arvid Rongve, Ingvild Saltvedt, Håvard K. Skjellegrind, Bo Engdahl, Ole A. Andreassen, Barbara Borroni, Patrizia Mecocci, Yehani Wedatilake, Richard Mayeux, Tatiana Foroud, Agustín Ruiz, Oscar L. Lopez, M. Ilyas Kamboh, Clive Ballard, Bernie Devlin, Constantine Lyketsos, Robert A. Sweet
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
affective disturbance
Alzheimer's disease
genome‐wide association
heritability
psychosis
Online Access:https://doi.org/10.1002/trc2.12472

Internet

https://doi.org/10.1002/trc2.12472

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