Population and breast cancer patients’ analysis reveals the diversity of genomic variation of the BRCA genes in the Mexican population

Population and breast cancer patients’ analysis reveals the diversity of genomic variation of the BRCA genes in the Mexican population

Abstract Interpretation of variants of unknown significance (VUS) in genetic tests is complicated in ethnically diverse populations, given the lack of information regarding the common spectrum of genetic variation in clinically relevant genes. Public availability of data obtained from high-throughpu...

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Bibliographic Details
Main Authors: J. C. Fernández-Lopez, S. Romero-Córdoba, R. Rebollar-Vega, L. A. Alfaro-Ruiz, S. Jiménez-Morales, F. Beltrán-Anaya, R. Arellano-Llamas, A. Cedro-Tanda, M. Rios-Romero, M. Ramirez-Florencio, V. Bautista-Piña, C. Dominguez-Reyes, F. Villegas-Carlos, A. Tenorio-Torres, A. Hidalgo-Miranda
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Human Genomics
Subjects:
BRCA
Breast cancer
Populations
Germline
Genetic testing
Online Access:http://link.springer.com/article/10.1186/s40246-018-0188-9

Internet

http://link.springer.com/article/10.1186/s40246-018-0188-9

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