The Fate of Epidermal Tight Junctions in the <i>stratum corneum</i>: Their Involvement in the Regulation of Desquamation and Phenotypic Expression of Certain Skin Conditions

The Fate of Epidermal Tight Junctions in the <i>stratum corneum</i>: Their Involvement in the Regulation of Desquamation and Phenotypic Expression of Certain Skin Conditions

We evaluated the presence of tight junction (TJ) remnants in the <i>stratum corneum</i> (SC) of in vitro reconstructed human epidermis and human skin explants subjected or not to an aggressive topical treatment with beta-lipohydroxy salicylic acid (LSA) for 24 h. LSA-treated samples show...

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Bibliographic Details
Main Authors: Marek Haftek, Vinzenz Oji, Laurence Feldmeyer, Daniel Hohl, Smaïl Hadj-Rabia, Rawad Abdayem
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
tight junction
<i>stratum corneum</i>
desquamation
peeling skin disease (PSD)
ichthyosis hypotrichosis sclerosing cholangitis (IHSC/NISCH) syndrome
ultrastructure
Online Access:https://www.mdpi.com/1422-0067/23/13/7486

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https://www.mdpi.com/1422-0067/23/13/7486

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