Brain effects of gestating germ-free persist in mouse neonates despite acquisition of a microbiota at birth

Brain effects of gestating germ-free persist in mouse neonates despite acquisition of a microbiota at birth

At birth, mammals experience a massive colonization by microorganisms. We previously reported that newborn mice gestated and born germ-free (GF) have increased microglial labeling and alterations in developmental neuronal cell death in the hippocampus and hypothalamus, as well as greater forebrain v...

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Bibliographic Details
Main Authors: Alexandra Castillo-Ruiz, Aviva Gars, Hannah Sturgeon, Nicole M. Ronczkowski, Dhanya N. Pyaram, Charlène J. G. Dauriat, Benoit Chassaing, Nancy G. Forger
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Neuroscience
Subjects:
cross-fostering
cell death
microglia
forebrain size
bacterial load
colonic content
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1130347/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1130347/full

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