Molecular features and predictive models identify the most lethal subtype and a therapeutic target for osteosarcoma

Molecular features and predictive models identify the most lethal subtype and a therapeutic target for osteosarcoma

BackgroundOsteosarcoma is the most common primary malignant bone tumor. The existing treatment regimens remained essentially unchanged over the past 30 years; hence the prognosis has plateaued at a poor level. Precise and personalized therapy is yet to be exploited.MethodsOne discovery cohort (n=98)...

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Bibliographic Details
Main Authors: Kun Zheng, Yushan Hou, Yiming Zhang, Fei Wang, Aihua Sun, Dong Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Oncology
Subjects:
osteosarcoma
molecular classification
cholesterol metabolism
drug target
SQLE
predictive model
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1111570/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1111570/full

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