Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time

Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time

Human pluripotent stem cell (hPSC)-derived progenies are immature versions of cells, presenting a potential limitation to the accurate modelling of diseases associated with maturity or age. Hence, it is important to characterise how closely cells used in culture resemble their native counterparts. I...

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Bibliographic Details
Main Authors: Grace E. Lidgerwood, Anne Senabouth, Casey J.A. Smith-Anttila, Vikkitharan Gnanasambandapillai, Dominik C. Kaczorowski, Daniela Amann-Zalcenstein, Erica L. Fletcher, Shalin H. Naik, Alex W. Hewitt, Joseph E. Powell, Alice Pébay
Format: Article
Language:English
Published: Oxford University Press 2021-04-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Human embryonic stem cell
Human pluripotent stem cell
Retinal pigment epithelium
Single-cell RNA sequencing
Ageing
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022920301352

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http://www.sciencedirect.com/science/article/pii/S1672022920301352

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