Enhanced survival of hypoimmunogenic otic progenitors following intracochlear xenotransplantation: repercussions for stem cell therapy in hearing loss models

Enhanced survival of hypoimmunogenic otic progenitors following intracochlear xenotransplantation: repercussions for stem cell therapy in hearing loss models

Abstract Stem cell replacement holds the potential for sensorineural hearing loss (SNHL) treatment. However, its translation into clinical practice requires strategies for improving stem cell survival following intracochlear transplantation. Considering recent findings showing that the inner ear con...

Full description

Bibliographic Details
Main Authors: Luisa H. Andrade da Silva, Rachel A. Heuer, Christian B. Roque, Tammy L. McGuire, Tomonori Hosoya, Hironobu Kimura, Kouichi Tamura, Akihiro J. Matsuoka
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Stem Cell Research & Therapy
Subjects:
Inner ear regeneration
Stem cell transplantation
Xenorejection
Gene engineering
Hypoimmunogenic derivatives
Online Access:https://doi.org/10.1186/s13287-023-03304-9

Internet

https://doi.org/10.1186/s13287-023-03304-9

Similar Items