MiR-144-3p inhibits gastric cancer progression and stemness via directly targeting GLI2 involved in hedgehog pathway

MiR-144-3p inhibits gastric cancer progression and stemness via directly targeting GLI2 involved in hedgehog pathway

Abstract Background Gastric cancer (GC) is the fifth most commonly diagnosed cancer worldwide. Due to the dismal prognosis, identifying novel therapeutic targets in GC is urgently needed. Evidences have shown that miRNAs played critical roles in the regulation of tumor initiation and progression. GL...

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Bibliographic Details
Main Authors: Yixun Lu, Benlong Zhang, Baohua Wang, Di Wu, Chuang Wang, Yunhe Gao, Wenquan Liang, Hongqing Xi, Xinxin Wang, Lin Chen
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Journal of Translational Medicine
Subjects:
Gastric cancer
GLI2
MiR-144-3p
Cancer stem cells
Online Access:https://doi.org/10.1186/s12967-021-03093-w

Internet

https://doi.org/10.1186/s12967-021-03093-w

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