Nuclear talin-1 provides a bridge between cell adhesion and gene expression

Nuclear talin-1 provides a bridge between cell adhesion and gene expression

Summary: Talin-1 (TLN1) is best known to activate integrin receptors and transmit mechanical stimuli to the actin cytoskeleton at focal adhesions. However, the localization of TLN1 is not restricted to focal adhesions. By utilizing both subcellular fractionations and confocal microscopy analyses, we...

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Bibliographic Details
Main Authors: Alejandro J. Da Silva, Hendrik S.E. Hästbacka, Mikael C. Puustinen, Jenny C. Pessa, Jens C. Luoto, Erika Sundström, Benjamin T. Goult, Guillaume Jacquemet, Eva Henriksson, Lea Sistonen
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:iScience
Subjects:
properties of biomolecules
cellular physiology
molecular biology
molecular interaction
cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225000045

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http://www.sciencedirect.com/science/article/pii/S2589004225000045

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