Structure, Activity and Function of the PRMT2 Protein Arginine Methyltransferase

PRMT2 belongs to the protein arginine methyltransferase (PRMT) family, which catalyzes the arginine methylation of target proteins. As a type I enzyme, PRMT2 produces asymmetric dimethyl arginine and has been shown to have weak methyltransferase activity on histone substrates in vitro, suggesting th...

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Bibliographic Details
Main Authors: Vincent Cura, Jean Cavarelli
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/11/1263