Estimating the sample size of sham-controlled randomized controlled trials using existing evidence [version 2; peer review: 2 approved]
Background: In randomized controlled trials (RCTs), the power is often ‘reverse engineered’ based on the number of participants that can realistically be achieved. An attractive alternative is planning a new trial conditional on the available evidence; a design of particular interest in RCTs that us...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2022-11-01
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| Series: | F1000Research |
| Subjects: | |
| Online Access: | https://f1000research.com/articles/11-85/v2 |