Oxygen therapy attenuates neuroinflammation after spinal cord injury

Abstract Acute hyperbaric O2 (HBO) therapy after spinal cord injury (SCI) can reduce inflammation and increase neuronal survival. To our knowledge, it is unknown if these benefits of HBO require hyperbaric vs. normobaric hyperoxia. We used a C4 lateralized contusion SCI in adult male and female rats...

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Bibliographic Details
Main Authors: Michael D. Sunshine, Victoria E. Bindi, Branden L. Nguyen, Vivian Doerr, Franccesco P. Boeno, Vijayendran Chandran, Ashley J. Smuder, David D. Fuller
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-023-02985-6