Quantitative analysis of amorphous form in indomethacin binary polymorphic mixtures using infrared spectroscopy analytical techniques combined with chemometrics methods
Pharmaceutical corporations prefer amorphous active pharmaceutical ingredients (APIs) because of their high apparent solubility and bioavailability, which are caused by long-range disorder, large unit surface free energy, and easily wetted particle surfaces. APIs in amorphous form tend to recrystall...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-08-01
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| Series: | Arabian Journal of Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535223003477 |