Knee Osteoarthritis Progression Is Delayed in Silent Information Regulator 2 Ortholog 1 Knock-in Mice

Knee Osteoarthritis Progression Is Delayed in Silent Information Regulator 2 Ortholog 1 Knock-in Mice

Overexpression of silent information regulator 2 ortholog 1 (SIRT1) is associated with beneficial roles in aging-related diseases; however, the effects of SIRT1 overexpression on osteoarthritis (OA) progression have not yet been studied. The aim of this study was to investigate OA progression in SIR...

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Bibliographic Details
Main Authors: Tetsuya Yamamoto, Nobuaki Miyaji, Kiminari Kataoka, Kyohei Nishida, Kanto Nagai, Noriyuki Kanzaki, Yuichi Hoshino, Ryosuke Kuroda, Takehiko Matsushita
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
silent information regulator 2 ortholog 1 (SIRT1)
osteoarthritis
knock-in mice
knee
Online Access:https://www.mdpi.com/1422-0067/22/19/10685

Internet

https://www.mdpi.com/1422-0067/22/19/10685

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