Characterization of rabbit myocilin: Implications for human myocilin glycosylation and signal peptide usage

<p>Abstract</p> <p>Background</p> <p>Mutations in the gene encoding human myocilin (<it>MYOC</it>) have been shown to cause juvenile- and adult-onset glaucoma. In addition, myocilin has been associated with glucocorticoid-induced ocular hypertension and ster...

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Bibliographic Details
Main Authors: Lotery Andrew J, Steely H Thomas, Sui Ruifang, Jacobson Nasreen, Shepard Allan R, Stone Edwin M, Clark Abbot F
Format: Article
Language:English
Published: BMC 2003-04-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/4/5