Extracellular matrix proteins in construction and function of in vitro blood-brain barrier models

The blood-brain barrier (BBB) is a highly impermeable barrier separating circulating blood and brain tissue. A functional BBB is critical for brain health, and BBB dysfunction has been linked to the pathophysiology of diseases such as stroke and Alzheimer’s disease. A variety of models have been dev...

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Bibliographic Details
Main Authors: Feifan Du, Eric V. Shusta, Sean P. Palecek
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Chemical Engineering
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fceng.2023.1130127/full