A protective and safe intranasal RSV vaccine based on a recombinant prefusion-like form of the F protein bound to bacterium-like particles.

A protective and safe intranasal RSV vaccine based on a recombinant prefusion-like form of the F protein bound to bacterium-like particles.

Respiratory syncytial virus (RSV) is an important cause of respiratory tract disease in infants and the elderly. Currently, no licensed vaccine against RSV is available. Here we describe the development of a safe and effective intranasal subunit vaccine that is based on recombinant fusion (F) protei...

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Bibliographic Details
Main Authors: Alan Rigter, Ivy Widjaja, Hanneke Versantvoort, Frank E J Coenjaerts, Maarten van Roosmalen, Kees Leenhouts, Peter J M Rottier, Bert Jan Haijema, Cornelis A M de Haan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3741363?pdf=render

Internet

http://europepmc.org/articles/PMC3741363?pdf=render

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