IL-15 Enhances Activation and IGF-1 Production of Dendritic Epidermal T Cells to Promote Wound Healing in Diabetic Mice

IL-15 Enhances Activation and IGF-1 Production of Dendritic Epidermal T Cells to Promote Wound Healing in Diabetic Mice

Altered homeostasis and dysfunction of dendritic epidermal T cells (DETCs) contribute to abnormal diabetic wound healing. IL-15 plays important roles in survival and activation of T lymphocytes. Recently, reduction of epidermal IL-15 has been reported as an important mechanism for abnormal DETC home...

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Bibliographic Details
Main Authors: Yangping Wang, Yang Bai, Yashu Li, Guangping Liang, Yufeng Jiang, Zhongyang Liu, Meixi Liu, Jianlei Hao, Xiaorong Zhang, Xiaohong Hu, Jian Chen, Rupeng Wang, Zhinan Yin, Jun Wu, Gaoxing Luo, Weifeng He
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Immunology
Subjects:
wound healing
dendritic epidermal T cell
IL-15
IGF-1
diabetes mellitus
type 1
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01557/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01557/full

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