Generator based approach to analyze mutations in genomic datasets

Abstract In contrast to the conventional approach of directly comparing genomic sequences using sequence alignment tools, we propose a computational approach that performs comparisons between sequence generators. These sequence generators are learned via a data-driven approach that empirically compu...

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Bibliographic Details
Main Authors: Siddharth Jain, Xiongye Xiao, Paul Bogdan, Jehoshua Bruck
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-00609-8