The Tryptophan Metabolite Indole-3-Carboxaldehyde Alleviates Mice with DSS-Induced Ulcerative Colitis by Balancing Amino Acid Metabolism, Inhibiting Intestinal Inflammation, and Improving Intestinal Barrier Function

The Tryptophan Metabolite Indole-3-Carboxaldehyde Alleviates Mice with DSS-Induced Ulcerative Colitis by Balancing Amino Acid Metabolism, Inhibiting Intestinal Inflammation, and Improving Intestinal Barrier Function

Ulcerative colitis (UC) has attracted much attention for its negative influence on quality of life and increased risk of colorectal cancer. Chemical and biological drugs are currently the usual treatment for UC. These drugs always induce severe side effects, or patients might become resistant to the...

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Bibliographic Details
Main Authors: Mingfei Liu, Yuxuan Wang, Haixin Xiang, Meng Guo, Shirong Li, Ming Liu, Jingchun Yao
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
colitis
3-IAld
anti-inflammatory
intestinal barrier
Online Access:https://www.mdpi.com/1420-3049/28/9/3704

Internet

https://www.mdpi.com/1420-3049/28/9/3704

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