The role of XCR1 and its ligand XCL1 in antigen cross-presentation by murine and human dendritic cells

Recently, the chemokine receptor XCR1 has been found to be exclusively expressed on a subset of DC known to be involved in antigen cross-presentation. This review aims to summarize the known biology of the XCR1 receptor and its chemokine ligand XCL1, both in the mouse and the human. Further, any inv...

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Bibliographic Details
Main Authors: Richard A. Kroczek, Volker eHenn
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00014/full