Interferon-γ release assay screening in biologics: safe and reliable, but not perfect

Interferon-γ release assay screening in biologics: safe and reliable, but not perfect

Background Systemic biologic agents can increase the risk of re-activation of latent tuberculosis (TB). Prior to initiation, screening for latent TB using an interferon-γ release assay (IGRA) is recommended. There is concern that false-negative IGRAs may be more likely in this context. Methods This...

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Main Authors: John Cafferkey, Yorissa Padayachee, Sophia Kostich, Kartik Kumar, Paul Jewell, Mikin Patel, Aneeka Chavda, Alison Cox, Mirae Park, Georgina Russell, Meg Coleman, Laura Martin, Onn Min Kon
Format: Article
Language:English
Published: European Respiratory Society 2022-11-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/8/4/00193-2022.full

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http://openres.ersjournals.com/content/8/4/00193-2022.full

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