Synergistic combination of doxorubicin with hydralazine, and disulfiram against MCF-7 breast cancer cell line.

Disulfiram and hydralazine have recently been reported to have anti-cancer action, and repositioned to be used as adjuvant in cancer therapy. Chemotherapy combined with other medications, such as those that affect the immune system or epigenetic cell profile, can overcome resistance with fewer adver...

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Bibliographic Details
Main Authors: Zainab Lafi, Walhan Alshaer, Lobna Gharaibeh, Dana A Alqudah, Baidaa AlQuaissi, Banan Bashaireh, Abed Alqader Ibrahim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0291981