The role of the two splice variants and extranuclear pathway on Ki-67 regulation in non-cancer and cancer cells.

Ki-67 is a nuclear protein that has been used in cancer diagnostic because of its specific cell-cycle dependent expression profile. After quantifying and characterising the expression level of Ki-67, as a function of the cell cycle, we found out that the two main splice variants of the protein (i.e....

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Bibliographic Details
Main Authors: Luca Chierico, Loris Rizzello, Lijuan Guan, Adrian Steve Joseph, Andrew Lewis, Giuseppe Battaglia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0171815&type=printable