Distinct Patterns of HBV Integration and <i>TERT</i> Alterations between in Tumor and Non-Tumor Tissue in Patients with Hepatocellular Carcinoma

Distinct Patterns of HBV Integration and <i>TERT</i> Alterations between in Tumor and Non-Tumor Tissue in Patients with Hepatocellular Carcinoma

Although hepatitis B virus (HBV) integration into the cellular genome is well known in HCC (hepatocellular carcinoma) patients, its biological role still remains uncertain. This study investigated the patterns of HBV integration and correlated them with <i>TERT</i> (telomerase reverse tr...

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Bibliographic Details
Main Authors: Jeong-Won Jang, Hye-Seon Kim, Jin-Seoub Kim, Soon-Kyu Lee, Ji-Won Han, Pil-Soo Sung, Si-Hyun Bae, Jong-Young Choi, Seung-Kew Yoon, Dong-Jin Han, Tae-Min Kim, Lewis R. Roberts
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
hepatitis B virus
virus integration
liver cancer
telomerase
point mutation
Online Access:https://www.mdpi.com/1422-0067/22/13/7056

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https://www.mdpi.com/1422-0067/22/13/7056

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