ATF5 promotes malignant T cell survival through the PI3K/AKT/mTOR pathway in cutaneous T cell lymphoma

ATF5 promotes malignant T cell survival through the PI3K/AKT/mTOR pathway in cutaneous T cell lymphoma

BackgroundsCutaneous T cell lymphoma (CTCL) is a non-Hodgkin lymphoma characterized by skin infiltration of malignant T cells. The biological overlap between malignant T cells and their normal counterparts has brought obstacles in identifying tumor-specific features and mechanisms, limiting current...

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Bibliographic Details
Main Authors: Mengzhou Cao, Pan Lai, Xiangjun Liu, Fengjie Liu, Yao Qin, Ping Tu, Yang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
cancer pathogenesis
transcription factor
malignant T cell
phosphoinositide 3-kinase
endoplasmic reticulum stress
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1282996/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1282996/full

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