LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2.

LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2.

High cholesterol and diabetes are major risk factors for atherosclerosis. Regression of atherosclerosis is mediated in part by the Liver X Receptor (LXR) through the induction of genes involved in cholesterol transport and efflux. In the context of diabetes, regression of atherosclerosis is impaired...

Full description

Bibliographic Details
Main Authors: Maryem A Hussein, Elina Shrestha, Mireille Ouimet, Tessa J Barrett, Sarah Leone, Kathryn J Moore, Yann Hérault, Edward A Fisher, Michael J Garabedian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4545936?pdf=render

Internet

http://europepmc.org/articles/PMC4545936?pdf=render

Similar Items