Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation

Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation

Summary: Mitochondria constantly undergo fusion and fission events, referred as mitochondrial dynamics, which determine mitochondrial architecture and bioenergetics. Cultured cell studies demonstrate that mitochondrial dynamics are acutely regulated by phosphorylation of the mitochondrial fission or...

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Bibliographic Details
Main Authors: Miriam Valera-Alberni, Magali Joffraud, Joan Miro-Blanch, Jordi Capellades, Alexandra Junza, Loïc Dayon, Antonio Núñez Galindo, Jose L. Sanchez-Garcia, Armand Valsesia, Angelique Cercillieux, Flavia Söllner, Andreas G. Ladurner, Oscar Yanes, Carles Cantó
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Cell Reports
Subjects:
mitochondrial dynamics
Drp1
mitochondrial respiration
insulin resistance
brown adipose tissue
thermoneutrality
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721009992

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http://www.sciencedirect.com/science/article/pii/S2211124721009992

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