Antiseptic Functions of CGK012 against HMGB1-Mediated Septic Responses

Antiseptic Functions of CGK012 against HMGB1-Mediated Septic Responses

High mobility group box 1 (HMGB1), a protein with important functions, has been recognized as a potential therapeutic target for the treatment of sepsis. One possible mechanism for this is that inhibiting HMGB1 secretion can exert antiseptic effects, which can restore the integrity of the vascular b...

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Bibliographic Details
Main Authors: Yun Jin Park, Jong Beom Heo, Yoon-Jung Choi, Sanghee Cho, Taeho Lee, Gyu Yong Song, Jong-Sup Bae
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
CGK012
sepsis
HMGB1
endothelium
Online Access:https://www.mdpi.com/1422-0067/25/5/2976

Internet

https://www.mdpi.com/1422-0067/25/5/2976

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