Effects of amino acid substitutions in the VP2 B-C loop on antigenicity and pathogenicity of serotype Asia1 foot-and-mouth disease virus

Effects of amino acid substitutions in the VP2 B-C loop on antigenicity and pathogenicity of serotype Asia1 foot-and-mouth disease virus

<p>Abstract</p> <p>Background</p> <p>Foot-and-mouth disease virus (FMDV) exhibits a high degree of antigenic variability. Studies of the antigenic diversity and determination of amino acid changes involved in this diversity are important to the design of broadly protect...

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Bibliographic Details
Main Authors: Xue Mei, Wang Haiwei, Li Wan, Zhou Guohui, Tu Yabin, Yu Li
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Virology Journal
Subjects:
Foot-and-mouth disease virus
VP2
Antigenic variation
Replication ability
Virulence
Online Access:http://www.virologyj.com/content/9/1/191

Internet

http://www.virologyj.com/content/9/1/191

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