DNA copy number loss associated with pediatric urinary tract infection risk

Urinary tract infections (UTI), associated with vesicoureteral reflux (VUR), can lead to chronic kidney disease. Genetic alterations in the innate immune defenses contribute to UTI risk. We investigated a novel gene, Dachsous Cadherin-Related 1 ( DCHS1 ), in children with UTI. We determined absolute...

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Bibliographic Details
Main Authors: Aslam H Qureshi, Dong Liang, Jorge Canas, Jenaya Hooks, Samuel W Arrregui, Vijay Saxena, Robert Rooney, Vikki Nolan, Andrew L Schwaderer, David S Hains
Format: Article
Language:English
Published: SAGE Publishing 2020-08-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/1753425920917193