Proteomics and weighted gene correlated network analysis reveal glutamatergic synapse signaling in diazepam treatment of alcohol withdrawal

Proteomics and weighted gene correlated network analysis reveal glutamatergic synapse signaling in diazepam treatment of alcohol withdrawal

Background: Alcohol use disorder (AUD) is characterized by chronic excessive alcohol consumption, often alternating with periods of abstinence known as alcohol withdrawal syndrome (AWS). Diazepam is the preferred benzodiazepine for treatment of alcohol withdrawal syndrome under most circumstances, b...

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Bibliographic Details
Main Authors: Wan Kong, Shanqing Huang, Zikai Chen, Xiaolin Li, Shujing Liu, Zi Zhang, Ye Yang, Zhanzhang Wang, Xiuqing Zhu, Xiaojia Ni, Haoyang Lu, Ming Zhang, Zezhi Li, Yuguan Wen, Dewei Shang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Pharmacology
Subjects:
alcohol withdrawal
diazepam
glutamatergic synapse
proteome
weighted gene correlated network analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1111758/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.1111758/full

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