HepGentox: a novel promising HepG2 reportergene-assay for the detection of genotoxic substances in complex mixtures

Background In risk assessment, genotoxicity is a key factor to determine the safety for the consumer. Most in vitro genotoxicity assays were developed for the assessment of pure substances. However, in recent years more attention has been given to complex mixtures, where usually low amounts of a sub...

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Bibliographic Details
Main Authors: Elisabeth Pinter, Christina Friedl, Alexandra Irnesberger, Thomas Czerny, Tina Piwonka, Alfonso Peñarroya, Manfred Tacker, Elisabeth Riegel
Format: Article
Language:English
Published: PeerJ Inc. 2021-07-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/11883.pdf