Gender Differences in Bile Acids and Microbiota in Relationship with Gender Dissimilarity in Steatosis Induced by Diet and FXR Inactivation

Gender Differences in Bile Acids and Microbiota in Relationship with Gender Dissimilarity in Steatosis Induced by Diet and FXR Inactivation

Abstract This study aims to uncover how specific bacteria and bile acids (BAs) contribute to steatosis induced by diet and farnesoid X receptor (FXR) deficiency in both genders. A control diet (CD) and Western diet (WD), which contains high fat and carbohydrate, were used to feed wild type (WT) and...

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Bibliographic Details
Main Authors: Lili Sheng, Prasant Kumar Jena, Hui-Xin Liu, Karen M. Kalanetra, Frank J. Gonzalez, Samuel W. French, Viswanathan V. Krishnan, David A. Mills, Yu-Jui Yvonne Wan
Format: Article
Language:English
Published: Nature Portfolio 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01576-9

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https://doi.org/10.1038/s41598-017-01576-9

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