Synthetic Kavalactone Analogues with Increased Potency and Selective Anthelmintic Activity against Larvae of <em>Haemonchus contortus</em> In Vitro

Synthetic Kavalactone Analogues with Increased Potency and Selective Anthelmintic Activity against Larvae of <em>Haemonchus contortus</em> In Vitro

Kava extract, an aqueous rhizome emulsion of the plant <i>Piper methysticum</i>, has been used for centuries by Pacific Islanders as a ceremonial beverage, and has been sold as an anxiolytic agent for some decades. Kavalactones are a major constituent of kava extract. In a previous inves...

Full description

Bibliographic Details
Main Authors: H.M.P. Dilrukshi Herath, Aya C. Taki, Nghi Nguyen, José Garcia-Bustos, Andreas Hofmann, Tao Wang, Guangxu Ma, Bill C.H. Chang, Abdul Jabbar, Brad E. Sleebs, Robin B. Gasser
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Molecules
Subjects:
kavalactone
synthetic analogues
anthelmintic
in vitro-activity
<i>Haemonchus contortus</i>
Online Access:https://www.mdpi.com/1420-3049/25/8/2004

Internet

https://www.mdpi.com/1420-3049/25/8/2004

Similar Items