Therapeutic innovation: Inflammatory-reactive astrocytes as targets of inflammation

Therapeutic innovation: Inflammatory-reactive astrocytes as targets of inflammation

This study aimed to test pharmaceutical compounds targeting astrocytes showing inflammatory dysregulation. The primary rat brain cultures were treated with different batches of serum with or without microglia added to make the cells inflammatory-reactive. Lipopolysaccharide (LPS) and tryptase were u...

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Bibliographic Details
Main Authors: Elisabeth Hansson, Tony Werner, Ulrika Björklund, Eva Skiöldebrand
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:IBRO Reports
Subjects:
Astrocytes
Inflammation
Ca2+ signaling
Actin filament
(−)-Naloxone
(−)-Linalool
Levetiracetam
Online Access:http://www.sciencedirect.com/science/article/pii/S2451830116300085

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http://www.sciencedirect.com/science/article/pii/S2451830116300085

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