Activation of α7 nicotinic acetylcholine receptor promotes HIV-1 transcription

Activation of α7 nicotinic acetylcholine receptor promotes HIV-1 transcription

Alpha7 nicotinic acetylcholine receptor (α7 nAChR), a hub of the cholinergic anti-inflammatory pathway (CAP), is required for the treatment of inflammatory diseases. HIV-1 infection can upregulate the expression of α7 nAChR in T lymphocytes and affect the role of CAP. However, whether α7 nAChR regul...

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Bibliographic Details
Main Authors: Jing Wen, Caiqi Zhao, Jie Chen, Shuting Song, Zhekai Lin, Shitao Xie, Huaxin Qi, Jianhua Wang, Xiao Su
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Cell Insight
Subjects:
HIV-1
α7 nAChR
ROS
p38 MAPK
LMNB1
Online Access:http://www.sciencedirect.com/science/article/pii/S2772892722000256

Internet

http://www.sciencedirect.com/science/article/pii/S2772892722000256

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