Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations

Ball-milling is usually used to prepare co-amorphous drug–amino acid (AA) mixtures. In this study, co-amorphous drug–AA mixtures were produced using spray-drying, a scalable industrially preferred preparation method. The influence of the solvent type and solvent composition was investigated. Mixture...

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Bibliographic Details
Main Authors: Jaya Mishra, Thomas Rades, Korbinian Löbmann, Holger Grohganz
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Pharmaceutics
Subjects:
Online Access:http://www.mdpi.com/1999-4923/10/2/47