Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations

Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations

Ball-milling is usually used to prepare co-amorphous drug–amino acid (AA) mixtures. In this study, co-amorphous drug–AA mixtures were produced using spray-drying, a scalable industrially preferred preparation method. The influence of the solvent type and solvent composition was investigated. Mixture...

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Bibliographic Details
Main Authors:	Jaya Mishra, Thomas Rades, Korbinian Löbmann, Holger Grohganz
Format:	Article
Language:	English
Published:	MDPI AG 2018-04-01
Series:	Pharmaceutics
Subjects:	co-amorphous spray-drying salt formation process parameter stability
Online Access:	http://www.mdpi.com/1999-4923/10/2/47

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