Effect of Insertion and Deletion in the Meq Protein Encoded by Highly Oncogenic Marek’s Disease Virus on Transactivation Activity and Virulence

Effect of Insertion and Deletion in the Meq Protein Encoded by Highly Oncogenic Marek’s Disease Virus on Transactivation Activity and Virulence

Marek’s disease virus (MDV) causes malignant lymphoma in chickens (Marek’s disease, MD). Although MD is currently controlled by vaccination, MDV strains have continuously increased in virulence over the recent decades. Polymorphisms in Meq, an MDV-encoded oncoprotein that serves as a transcription f...

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Bibliographic Details
Main Authors: Jumpei Sato, Shiro Murata, Zhiyuan Yang, Benedikt B. Kaufer, Sotaro Fujisawa, Hikari Seo, Naoya Maekawa, Tomohiro Okagawa, Satoru Konnai, Nikolaus Osterrieder, Mark S. Parcells, Kazuhiko Ohashi
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Viruses
Subjects:
Marek’s disease virus
Marek’s disease
Meq
CVI988
tumorigenesis
pathogenicity
Online Access:https://www.mdpi.com/1999-4915/14/2/382

Internet

https://www.mdpi.com/1999-4915/14/2/382

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