Unfolded protein response (UPR) integrated signaling networks determine cell fate during hypoxia
Abstract During hypoxic conditions, cells undergo critical adaptive responses that include the up-regulation of hypoxia-inducible proteins (HIFs) and the induction of the unfolded protein response (UPR). While their induced signaling pathways have many distinct targets, there are some important conn...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-03-01
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Series: | Cellular & Molecular Biology Letters |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s11658-020-00212-1 |