Convergent imaging-transcriptomic evidence for disturbed iron homeostasis in Gilles de la Tourette syndrome

Convergent imaging-transcriptomic evidence for disturbed iron homeostasis in Gilles de la Tourette syndrome

Gilles de la Tourette syndrome (GTS) is a neuropsychiatric movement disorder with reported abnormalities in various neurotransmitter systems. Considering the integral role of iron in neurotransmitter synthesis and transport, it is hypothesized that iron exhibits a role in GTS pathophysiology. As a s...

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Bibliographic Details
Main Authors: Ahmad Seif Kanaan, Dongmei Yu, Riccardo Metere, Andreas Schäfer, Torsten Schlumm, Berkin Bilgic, Alfred Anwander, Carol A. Mathews, Jeremiah M. Scharf, Kirsten Müller-Vahl, Harald E. Möller
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Neurobiology of Disease
Subjects:
Gene expression
Iron
Magnetic susceptibility
MRI
Subcortical brain
Tourette syndrome
Online Access:http://www.sciencedirect.com/science/article/pii/S096999612300267X

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http://www.sciencedirect.com/science/article/pii/S096999612300267X

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