Ongoing repair of migration-coupled DNA damage allows planarian adult stem cells to reach wound sites

Mechanical stress during cell migration may be a previously unappreciated source of genome instability, but the extent to which this happens in any animal in vivo remains unknown. We consider an in vivo system where the adult stem cells of planarian flatworms are required to migrate to a distal woun...

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Bibliographic Details
Main Authors: Sounak Sahu, Divya Sridhar, Prasad Abnave, Noboyoshi Kosaka, Anish Dattani, James M Thompson, Mark A Hill, Aziz Aboobaker
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/63779